Sitagliptin Phosphate and Metformin Hydrochloride

Sitagliptin Phosphate and Metformin Hydrochloride Tablets
Sitagliptin and Metformin is prescribed to control high blood sugar levels in type 2 diabetes mellitus for adult patients above 18 years of age.

Sitagliptin and Metformin Dosage forms & Strength :-

• Sitagliptin Phosphate 25 mg tablets for oral use.
Sitagliptin Phosphate 50 mg tablets for oral use.
Sitagliptin Phosphate 100 mg tablets for oral use.
Sitagliptin Phosphate 50 mg Metformin Hydrochloride 500 mg tablets for oral use.
Sitagliptin Phosphate 50 mg Metformin Hydrochloride 1000 mg tablets for oral use.
Sitagliptin Phosphate 100 mg Metformin Hydrochloride 500 mg tablets for oral use.
Sitagliptin Phosphate 100 mg Metformin Hydrochloride 1000 mg tablets for oral use.
Sitagliptin Phosphate 50 mg Metformin Hydrochloride 850 mg tablets for oral use.

Sitagliptin and Metformin Uses :-

Sitagliptin and Metformin is an antidiabetic medicine. Sitagliptin and Metformin is used to control type 2 diabetes mellitus (high blood sugar levels) in adult patients above 18 years of age.
Sitagliptin and Metformin is also used alone or in combination with certain other antidiabetic medicines. (such as insulin, sulfonylurea or glitazone)
Sitagliptin and Metformin helps to increase the levels of insulin produced after a meal and decreases the amount of sugar made by the body.

Sitagliptin and Metformin Dosage :-

Sitagliptin and Metformin is a prescription medicine. Take Sitagliptin and Metformin as directed by your doctor. 
Sitagliptin and Metformin can be taken with food, and should be swallowed whole and tablets must not be split, crushed, or chewed before swallowing.
Do not take a higher or lower dose than directed by your doctor.
Neverr self-medicate or change the dosage without a doctor's advice.
Do not take 2 or more doses at the same time. Always try to take Sitagliptin and Metformin on regular schedule.
Always take the tablet even if you feel well or your blood sugar level is under control.
Do not stop taking without your doctor's advice. Otherwise, your blood sugar level may rise again. Do not stop taking Sitagliptin and Metformin without asking your doctor.
Because the treatment of diabetes is lifelong.

Sitagliptin and Metformin Side-effects :-

Like all medicines, Sitagliptin and Metformin can cause side effects, however not everyone may experience these side effects.
• Hypoglycaemia,
• Nausea,
• Vomiting,
• Flatulence,
Most of these side effects are short term and get resolved with time. Although, if any of these side effects do not resolve with time or get poor, take a doctor's consultation as soon as possible.

How Sitagliptin and Metformin Works :-

Sitagliptin and Metformin consists of : Sitagliptin & Metformin.
Sitagliptin phosphate is an dipeptidyl peptidase 4 (DPP-4) inhibitors.
Sitagliptin phosphate helps to increase the levels of insulin produced after a meal and decreases the amount of sugar made by the body.
Metformin is a biguanide. Metformin delays the absorption of glucose from the intestines, by reducing the production of glucose in the liver. Metformin works by increasing the sensitivity of the body to insulin.
Thus, Sitagliptin and Metformin that control high blood sugar levels in adult patients with type 2 diabetes mellitus.

Precautions & Warnings :-

• Do not take Sitagliptin and Metformin, if you are allergic to sitagliptin & metformin or any of the other ingredients of Sitagliptin and Metformin.
• Severe Kidney Impairment :
Sitagliptin and Metformin is not suggested for use in patients with a serious impairment of kidney function due to the grown risk of serious adverse effects.
• Metabolic Acidosis :
Sitagliptin and Metformin is not suggested for use in patients with metabolic acidosis  it can worsen the patient's condition.
• Pregnancy :
Sitagliptin and Metformin is not suggested for use in pregnant women untill it is necessary. All the risks and benefits must be discussed with the doctor before taking Sitagliptin and Metformin.
• Breast-feeding :
Sitagliptin and Metformin is not suggested for use in breastfeeding women untill it is necessary. All the risks and benefits must be discussed with the doctor before taking Sitagliptin and Metformin. Your doctor can suggest a safer alternative based on your clinical condition.
• Bullous Pemphigoid :
Sitagliptin and Metformin should be used with caution due to the grown risk of bullous pemphigoid, a hypersensitivity reaction of the skin. Any uncommon symptoms like skin blisters or skin rashes should be reported to the doctor on priority. Therapy with the medicine can be discontinued based on the clinical condition of the patient.
Sitagliptin and Metformin is not suggested for use in patients with a known history of diabetic ketoacidosis due to the grown risk of worsening of the patient's condition.
Sitagliptin and Metformin is not suggested for use in patients with type 1 diabetes mellitus.
• Kidney Disease :
Sitagliptin and Metformin should be used with caution in patients with a known history of kidney disease due to the grown risk of worsening of the patient's condition. Replacement with a suitable alternative can be needed based on the clinical condition of the patient.
• Alcohol Use :
Drinking of alcohol is not suggested during treatment with Sitagliptin and Metformin due to the grown risk of critical adverse effects.
• Stress :
Use of Sitagliptin and Metformin must be discontinued in patients exposed to stressful conditions like a fever, trauma, surgeries, or accidents since it can not be helpfull in controlling blood sugar levels in these conditions. Replacement with a suitable alternative should be considered under your doctor's supervision.
• Diarrhea :
Sitagliptin and Metformin can give rise to diarrhea when therapy is initiated. In most cases, diarrhea subsides by itself. Talk your doctor if the problem continue for longer durations. Therapy can need to be discontinued in some cases based on the clinical condition.
• Vitamin B12 Deficiency :
Sitagliptin and Metformin must be used with very caution in patients with vitamin B12 deficiency since it can worsen the patient's condition. Appropriate vitamin B12 supplementation and dose adjustments can be needed in some cases.
• Pancreatitis :
Drinking of alcohol is not suggested during treatment with Sitagliptin and Metformin due to the grown risk of critical adverse effects. must be used with very caution in patients with a known history of pancreatitis due to the grown risk of recurrent pancreatitis. Report any symptoms like  abdominal pain, nausea, vomiting, etc. to the doctor immediately. Therapy with the medicine can be discontinued based on the clinical condition of the patient.
• Renal Dysfunction :
Drinking of alcohol is not suggested during treatment with Sitagliptin and Metformin due to the grown risk of critical adverse effects. must be used with very caution in patients with a history of kidney diseases due to the grown risk of worsening of the patient's condition. Replacement with a suitable alternative can be needed based on the clinical condition.
• Lactic Acidosis :
This medicine can give rise to lactic acidosis in some patients. This risk is mostly higher in patients with kidney diseases, heart diseases, or septicemia. Close monitoring of blood glucose levels, kidney function, heart function, and liver function can be needed for such patients based on the clinical condition. Report any symptoms like fatigue, breathing difficulty, increased sleep, nausea, vomiting, diarrhea, irregular heartbeat, etc. to the doctor immediately. Appropriate corrective measures and discontinuation of therapy can be needed in some cases based on the clinical condition.
• Sitagliptin and Metformin is not suggested for use in children and adolescents since the safety and efficacy of use are not clinically established.

Sitagliptin and Metformin Brand Name :-


Sitagliptin and Metformin Price :-

MRP ₹ = 

Sitagliptin and Metformin Storage :-

Sitagliptin and Metformin : store below 30°C
Therapeutics Indiaction : Treatment of type 2 diabetes mellitus.

FAQs :-

What is Sitagliptin and Metformin?
Sitagliptin and Metformin medicine consist Sitagliptin and Metformin . Sitagliptin and Metformin is use in the treatment of type 2 diabetes mellitus.

How should Sitagliptin and Metformin be taken?
Sitagliptin and Metformin can be taken with food. Always try to take Sitagliptin and Metformin on regular schedule. Always take the tablet even if you feel well or your blood sugar level is under control. Do not stop taking without your doctor's advice.

What are the side effects of Sitagliptin and Metformin?
Sitagliptin and Metformin can cause some side effects such as, hypoglycaemia, nausea, vomiting and flatulence etc. Most of these side effects are short term and get resolved with time. 

What if I forget to take Sitagliptin and Metformin?
If you miss a dose of Sitagliptin and Metformin, take Sitagliptin and Metformin as soon as you remember. Do not take 2 or more doses at the same time. Always try to take Sitagliptin and Metformin on regular schedule.

Sitagliptin and Metformin can be taken during pregnancy?
Sitagliptin and Metformin is not suggested for use in pregnant women untill it is necessary. All the risks and benefits must be discussed with the doctor before taking Sitagliptin and Metformin.

Sitagliptin and Metformin can be taken while breast-feeding?
Sitagliptin and Metformin is not suggested for use in breastfeeding women untill it is necessary. All the risks and benefits must be discussed with the doctor before taking Sitagliptin and Metformin. Your doctor can suggest a safer alternative based on your clinical condition.
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