Nodular Vasculitis (नोड्यूलर वास्कुलिटिस) एक rare inflammatory skin disorder है जिसमें subcutaneous fat और small blood vessels (vasculitis) में inflammation होता है।
- यह condition मुख्य रूप से legs (पाँव) में painful nodules के रूप में दिखाई देती है।
- Lesions अक्सर ulcerate और crusting के साथ होते हैं।
- Immunologic reaction और infectious triggers इसका मुख्य कारण माना जाता है।
- कभी-कभी इसे erythema induratum से भी relate किया जाता है।
Nodular Vasculitis क्या है (What is Nodular Vasculitis)
- Chronic inflammatory condition affecting subcutaneous fat and blood vessels
- Typically manifests as tender, erythematous nodules, mostly on posterior legs
- Often associated with ulceration, crusting, and secondary infection
- Slow-healing lesions, sometimes recurrent
Nodular Vasculitis कारण (Causes of Nodular Vasculitis)
1. Infectious Triggers
- Mycobacterium tuberculosis (especially in erythema induratum type)
- Other bacterial or viral infections
2. Immunologic / Autoimmune Factors
- Abnormal immune response to infections or medications
- Small vessel vasculitis and immune complex deposition
3. Idiopathic
- Many cases occur without identifiable cause
4. Other Risk Factors
- Female gender (more common in women)
- Age 20–50 years
Nodular Vasculitis लक्षण (Symptoms of Nodular Vasculitis)
- Painful nodules on lower legs (especially calves)
- Nodules may ulcerate and crust
- Lesions tender to touch
- Red to violaceous in color
- Occasionally systemic symptoms: mild fever, fatigue
- Recurrent episodes over months to years
Symptoms often mimic other vasculitic or infectious skin disorders।
Nodular Vasculitis कैसे पहचाने (Diagnosis of Nodular Vasculitis)
- Physical Examination – tender subcutaneous nodules, ulceration
- Skin Biopsy – shows lobular panniculitis with vasculitis
- Blood Tests – rule out systemic autoimmune disorders (ANA, CRP, ESR)
- Microbiological Tests – TB tests if infectious cause suspected
- Imaging (rarely) – ultrasound to assess depth of lesions
Histopathology is key for definitive diagnosis।
Nodular Vasculitis इलाज (Treatment of Nodular Vasculitis)
1. Address Underlying Cause
- Anti-tubercular therapy (ATT) if TB-associated
- Treat secondary bacterial infections
2. Anti-inflammatory Therapy
- Corticosteroids (topical or systemic)
- NSAIDs for pain and inflammation
3. Immunosuppressive Therapy (Severe/Refractory Cases)
- Azathioprine or methotrexate in chronic, recurrent cases
4. Supportive Care
- Wound care for ulcerated lesions
- Compression stockings if edema present
- Elevation of legs to reduce inflammation
5. Lifestyle Measures
- Avoid trauma to affected areas
- Maintain good hygiene
- Balanced nutrition to promote healing
Early treatment helps prevent chronic ulceration and scarring।
रोकथाम (Prevention)
- Prompt treatment of underlying infections
- Avoid injury or trauma to lower legs
- Maintain good hygiene and skin care
- Regular monitoring in patients with history of recurrent nodular lesions
सावधानियाँ (Precautions)
- Do not ignore painful, recurrent nodules on legs
- Avoid self-medication or topical irritants
- Follow prescribed antibiotic, anti-inflammatory, or immunosuppressive therapy
- Regular follow-up to monitor healing and prevent complications
FAQs (अक्सर पूछे जाने वाले प्रश्न)
Q1. Nodular Vasculitis contagious है?
नहीं, यह directly contagious नहीं है; हालांकि underlying infection जैसे TB treat करना जरूरी है।
Q2. क्या यह cancer है?
नहीं, यह benign inflammatory disorder है।
Q3. Recurrence common है?
हाँ, especially if underlying cause untreated या chronic immune response present हो।
Q4. कितने समय में ठीक हो जाता है?
Mild cases weeks में improve हो सकते हैं, severe/ulcerated lesions months तक last कर सकते हैं।
निष्कर्ष (Conclusion)
Nodular Vasculitis (नोड्यूलर वास्कुलिटिस) एक rare inflammatory disorder है जो lower legs में painful nodules और ulceration का कारण बनता है।
Early diagnosis, treatment of underlying infection, anti-inflammatory therapy और proper wound care से recovery तेज और recurrence कम होती है।
अगर किसी को persistent painful nodules, ulceration या crusting दिखाई दे, तो तुरंत dermatologist या physician से consultation जरूरी है।